The 2022 FIFA World Cup qualification is the qualifying process which will decide 31 of the 32 teams that will participate in the 2022 FIFA World Cup, joining hosts Qatar, who received an automatic spot.
Parallel tournaments are organised by FIFA's six confederations. Qualification started on 6 June 2019, when the first match played was between Mongolia and Brunei and the first goal was scored by Mongolian player Norjmoogiin Tsedenbal, and is set to end in June 2022 with the inter-confederation play-offs. Unlike with previous editions, there was no general preliminary draw, and instead, various draws were held separately due to different timelines used by each confederation. The qualification process has suffered numerous postponements due to the COVID-19 pandemic.
CAF
CAF announced on 10 July 2019 a reversion to the format used for its 2014 FIFA World Cup qualification competition.
- First round: 28 teams (ranked 27–54) played home-and-away over two legs. The fourteen winners advanced to the second round.
- Second round: 40 teams (teams ranked 1–26 and fourteen first round winners) were divided into ten groups of four teams to play home-and-away round-robin matches. The ten group winners advanced to the third round.
- Third round: Ten teams that had advanced from the second round played home-and-away over two legs. The five winners qualified for the World Cup.
Third round
1-1 1–4 
0-1 2–1 (a) 
0-1 0–0 
1-0 0–1 (1–3 p) 
0-0 1–1 (a) 
Qualified teams
The following five teams from CAF qualified for the final tournament.
| Team | Qualified as | Qualified on | Previous appearances in FIFA World Cup |
|---|---|---|---|
 Ghana | Third round winners | 29 March 2022 | 3 (2006, 2010, 2014) |
 Senegal | Third round winners | 29 March 2022 | 2 (2002, 2018) |
 Tunisia | Third round winners | 29 March 2022 | 5 (1978, 1998, 2002, 2006, 2018) |
 Morocco | Third round winners | 29 March 2022 | 5 (1970, 1986, 1994, 1998, 2018) |
 Cameroon | Third round winners | 29 March 2022 | 7 (1982, 1990, 1994, 1998, 2002, 2010, 2014) |